Frequently Asked Questions:

gammaCore is intended for preventative and acute migraine treatment in adolescents and adults ages 12 and up, as well as adult acute and preventative treatment of cluster headache, treatment of hemicrania continua and paroxysmal hemicrania. For full indication and important safety information, click visit

Yes, gammaCore has 7 different FDA clearances with robust scientific and clinical data to support it’s safe and effective use, including:

  • 7 randomized controlled clinical trials
  • >30 mechanism of action peer reviewed papers, and
  • >40 peer reviewed clinical papers

For more information on our clinical studies, see

When using gammaCore, you should feel a tingling sensation on the neck where the device is held. You may feel a downward pulling on your lip- this is the most common muscle contraction seen with gammaCore use and indicates you’re in the correct treatment position. The user controls the intensity level and can increase or decrease at any time. Treatment should never be painful.

Depending on the type of headache you are treating, initial treatments can last anywhere from 4 to 6 minutes. If needed, treatments can be repeated if additional attack occurs and can be used for multiple attacks per day. Learn more about treatment timing at

We recommend using the highest intensity level comfortably tolerated. This number is different for everyone, users typically feel optimal intensity between 15 and 25. For best results, raise the intensity to a level where you feel a slight “lip pull” sensation.

Yes, gammaCore is safe to use with any other prescribed or over the counter medication.

The gammaCore SapphireTM device comes preloaded with 3 months (93 days) of consecutive treatment. Each day the device allows up to 24 stimulations, so you can treat multiple attacks, if needed. If obtaining your device through the VA, treatment duration may vary.

gammaCore is a safe and well-tolerated non-drug treatment. Most side effects are mild, occur while using the device, and disappear soon after each treatment. In clinical studies, <5% of participants experienced mild side effects, including but not limited to:

  • Application site discomfort, irritation, and redness
  • Muscle twitching and/or contractions
  • Local pain, face/head/neck area (including toothache)
  • Headache
  • Dizziness
  • Tingling, pricking, or a feeling of “pins and needles” on the skin where the device is applied

It is safe to travel with gammaCore. The device contains a lithium battery, we recommend storing gammaCore in your carry-on luggage to assure it is not exposed to extreme conditions. One tube of conductive gel is within the TSA liquid carry on regulation.

See the comparison chart below for some differences between gammaCore and other treatments.

*Always speak with your healthcare provider to determine the best option for you.

gammaCore is available by prescription only. If you have a prescription, fax it to 855-647-1320 or email If you need a prescription, download the prescription form and have your healthcare provider send it over.

Prefer to find a provider near you? Check out our health care finder at

Active duty personal and veterans can obtain a prescription through the VA, to learn more about the process at

Find a health care provider near you and ask about gammaCore