One Device. Many Uses.

gammaCore Device

gammaCore Sapphire is the first and only FDA cleared drug-free non-invasive device to treat and prevent migraine and cluster headache pain via the vagus nerve. It's small, handheld and portable for quick and easy treatments whenever and wherever needed.

For acute migraine use: Treat right away. With a few 2-minute treatments, you could see fast acting, long-lasting pain relief, with results in as little as 30 minutes and lasting up to 48 hours.

To prevent future migraines, simply treat 3 times a day for more headache free days, so you can live life with less disruption. No pills, no injections or drug like side effects.

How It Works

Unlike traditional vagus nerve stimulation, gammaCore non-invasive vagus nerve stimulator (nVNS) activates the vagus nerve with gentle electrical stimulation through the skin to prevent and relieve headache pain, without the need for surgery.

Why simulate the vagus nerve? Think of the vagus nerve as the “superhighway” of the nervous system. This important highway sends communications between your brain and many parts of the body.

Stimulating the vagus nerve blocks the pain signals causing the attacks, to help provide fast relief and prevent future attacks.

Vagus nerve stimulation animation.

See How gammaCore Is Changing Lives

*Individual results may vary

Getting Started With gammaCore Is Easy!

get started

Step 1

Download the prescription form.


Step 2

Have your healthcare provider complete the form, then email the completed form to or fax 1-855-647-1320.

Ship gammacore

Step 3

Once received, we will reach out within 1-3 days to confirm details.

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Find a health care provider near you and ask about gammaCore