How to Relieve Migraine with gammaCore

If you suffer from migraines, you know all too well how debilitating they can be. The throbbing pain, nausea, and sensitivity to light and sound can make even the simplest tasks feel impossible. But what if there was a way to get migraine relief and prevent future attacks without relying solely on medication? gammaCore™ non-invasive vagus nerve stimulator (nVNS) might be the answer you’ve been looking for.

What Is the Vagus Nerve?

Before getting into gammaCore nVNS and how it can help with your migraine pain, let’s start by breaking down the vagus nerve, the most complex cranial nerve in your body. The vagus nerve runs from your brain to your abdomen and branches to the heart, lungs, stomach, and other organs. Many would consider the vagus nerve to be like the nervous system’s “super-highway,” sending important communication between your brain and many parts of the body. It plays a crucial role in many vital functions within the body, including pain regulation, digestion, heart rate, immunity, and stress.

How Does gammaCore Work?

gammaCore provides clinically proven, reliable relief from migraine pain by gently stimulating the vagus nerve. It is a portable, easy-to-use medical device with 6 FDA-cleared indications for headache.1 It can be used to prevent headache pain before it starts or quickly stop painful attacks when they happen. gammaCore is available with a prescription from your health care provider, but you can administer it yourself at home.

During treatments, the device is placed on the neck, where the vagus nerve is located, and sends gentle electrical energy non-invasively through the skin. The electrical energy stimulates the vagus nerve and begins sending messages to the brain. Since the vagus nerve plays an important role in regulating pain, stimulating the vagus nerve can block signals that cause headache pain and prevent future migraine attacks before they happen.

Treatments with gammaCore are proven to be safe and well-tolerated. Clinical trials have demonstrated no serious device-related side effects. Most side effects, if any, were mild, occurred during the use of the device, and went away quickly after each treatment. The most common side effects occurred in less than 5% of patients.

Quick and Easy Treatments for Migraine Relief

Use gammaCore twice daily to keep migraines at bay and as needed (up to 24 times daily) for fast-acting migraine relief when you need it.

  • Preventive Treatments: A treatment consisting of 2 two-minute stimulations on the same side of the neck morning and night.
  • As Needed Treatments: A treatment consisting of 2 two-minute stimulations on the same side of the neck as needed; repeat treatment if pain persists.

gammaCore. One Device. Many Benefits.

By reducing migraine symptoms, gammaCore can help you regain control of your life and enjoy activities you may previously have had to avoid due to your painful migraines. With gammaCore, you’ll be able to enjoy:

  • Reduced Migraine Attacks: Several studies have shown that gammaCore can effectively reduce the frequency and severity of migraine attacks, allowing you to enjoy more pain-free days.2,3,4
  • Drug-Free Pain Relief: Unlike some migraine medications, gammaCore is a non-drug treatment, which means no pills, injections, or drug-like side effects. It’s also safe to use with other medications or treatments.
  • Convenience: You can use gammaCore in the comfort of your home, making it a convenient and accessible option for migraine management. Also, because it’s portable and handheld, it’s easy to take with you on the go if a migraine strikes while you’re out.

To see if gammaCore is right for you, visit our physician finder to locate a health care provider near you, or contact our dedicated Customer Experience team at 888-903-2673 or

1. gammaCore Instructions for Use. (2023). electroCore, Inc.
2. Diener HC, Goadsby PJ, Ashina M, et al. (2019). Non-invasive vagus nerve stimulation (nVNS) for the preventive treatment of episodic migraine: the multicenter, double-blind, randomized, sham-controlled PREMIUM trial. Cephalalgia, 39(12).
3. Silberstein SD, Calhoun AH, Lipton RB, et al. (2018). Chronic migraine headache prevention with noninvasive vagus nerve stimulation: the EVENT study. Neurology, 87(5).
4. Tassorelli C, Grazzi L, de Tommaso M, et al. (2018). Non-invasive vagus nerve stimulation as acute therapy for migraine: the randomized PRESTO study. Neurology, 91(4).