The burden of cluster headache

What is cluster headache?

Cluster headache has been called one of the most painful conditions known to mankind. Sufferers typically experience a severe stabbing pain on one side of the face, usually centered over one eye, one temple, or forehead.

The pain is often experienced at a similar time each day. Then pain usually reaches full intensity rapidly and can last from 15-180 minutes. A blocked or runny nose, drooping eyelid, or tearing can also be experienced with an attack.

What are the two types?

People can suffer from episodic or chronic cluster headaches. Most sufferers —80%-90%— have episodic cluster headache. While episodic cluster headache has alternating periods with or without attacks, chronic cluster headache normally occurs for 1 year or longer without remission or with remission periods lasting less than 3 months.

Patients are looking for a new approach to treatment

Despite the debilitating nature of cluster headache, many patients are not satisfied with their current treatment options, and they need new treatments. A recent survey revealed deep dissatisfaction among cluster headache sufferers.*

Patient-Reported Satisfaction With Current Acute Treatments (n=291)


of respondents felt their current acute treatments were not easy or convenient to use


of respondents said safety was a concern in selecting a treatment option


of respondents expressed a desire for new acute treatments

  • Survey conducted by ClusterBusters in October of 2016 to assess the impressions and perspectives on current treatments and interest in new acute treatment options. A total of 291 subjects participated in the survey, with 177 of them suffering from episodic cluster headaches, 111 suffering from chronic cluster headaches, and 3 who did not respond.