One Device. Many Uses.

gammaCore Device

gammaCore SapphireTM is the first and only FDA cleared non-invasive device to treat and prevent multiple types of headache pain via the vagus nerve. It’s small, handheld and portable for quick and easy treatments whenever and wherever needed.

For acute use:

Treat right away and with a few 2-minute treatments, you could see fast acting, long-lasting pain relief.

To prevent future headache pain:

Simply treat 2 times a day (morning and night) for more headache-free days, so you can live life with less disruption.

Safe, Effective and Easy to Use Treatment For



Clinically proven to treat and prevent migraines in users ages 12 and up. Help reduce migraines days without additional drugs.

Cluster Headache

Cluster Headache

The only clinically proven device to treat and prevent cluster headache attacks, while providing fast, reliable relief for those suffering with cluster headache.

Hemicrania Continua (HC) & Paroxysmal Hemicrania (PH)

Hemicrania Continua (HC) & Paroxysmal Hemicrania (PH)

First and ONLY device for Hemicrania Continua and Paroxysmal Hemicrania treatment, proven to reduce pain severity or headache frequency.

How It Works

Unlike traditional vagus nerve stimulation, gammaCore non-invasive vagus nerve stimulator (nVNS) activates the vagus nerve with gentle electrical stimulation through the skin to prevent and relieve headache pain, without the need for surgery.

Why stimulate the vagus nerve? Think of the vagus nerve as the “superhighway” of the nervous system. This important highway sends communications between your brain and many parts of the body.

Stimulating the vagus nerve blocks the pain signals causing the attacks, to help provide fast relief and prevent future attacks.

Vagus nerve stimulation animation.

See How gammaCore Is Changing Lives

*Individual results may vary

Featured In

How gammaCore (nVNS) Works
gammaCore featured in Forbes

“Digital Health’s
Big Secret”

gammaCore featured in Men's Health

“gammaCore can be used as often as you need, isn’t invasive, and doesn’t come with the side effects of other treatments”

gammaCore featured on Good Morning America

“Cutting-Edge Treatments
for Migraines”

gammaCore featured on The Dr. Oz Show

“The Best Advances to Stop Chronic Headaches”

Ready to Get Started? Here's How

get started

Step 1

Download the prescription form.


Step 2

Have your healthcare provider complete the form, then email the completed form to or fax 1-855-647-1320.

Ship gammacore

Step 3

Once received, we will reach out within 1-3 days to confirm details.

gammaCore may be HSA or FSA Eligible

Your gammaCore expenses may be eligible for reimbursement through your Health Savings Account (HSA) or Flexible Saving Account (FSA). Ask us for more details!

Find a health care provider near you and ask about gammaCore